According to the Centers for Disease Control and Prevention (CDC), cigarette smoking is responsible for more than 480,000 deaths in the U.S. annually, including more than 41,000 deaths from second-hand smoke. Smoking is also the leading cause of preventable deaths and affects nearly every organ in the body. Tobacco use is also very expensive. In 2014, the Department of Defense spent almost $1.8 billion in associated medical and non-medical costs.